Heiti verkefnis: Preparation and pharmacokinetic evaluation of self-assembly of drug/cyclodextrin nanoparticles with specific administration properties.
Um verkefnið: The project is a part of an EU funded joint research training project “Novel multifunctional cyclodextrin-based nanocarriers for drug encapsulation and delivery as a strategy to overcome current therapeutic drawbacks” (grant agreement N° 237962).
The work involves preparation of self-associating cyclodextrin/drug complexes, cyclodextrin-polymer/drug complexes, self-assembling cyclodextrin/polymer nanoparticles; evaluation of their drug loading, drug release, particle size, morphology, stability. The focus is on parenteral drug delivery of anticancer drugs with nanoparticles of specific size and stability aiming for enhanced permeation and retention (EPR) effect.
Leiðbeinandi: Þorsteinn Loftsson
M.Sc. in Chemical Engineering, 2011 Faculty of Chemical Engineering and Bioengineering, Budapest University of Technology and Economics, Budapest, Hungary